Cayman Chemical ANTIBODY ZB716 500ug
An ERα degrader (IC50 = 4.1 nM); inhibits estradiol-induced ERα transcriptional activity in a reporter assay using T47D cells at 1 or 10 nM; decreases the proliferation of MCF-7 and T47D cells and tamoxifen-resistant MCF-7 and T47D cells (IC50s = 0.0032, 0.0062, 0.069, and 0.037 nM, respectively)